Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN2 | P17655 | 12/20 | 0.54 |
| ▸ | MMP1 | P03956 | 6/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MMP3 | P08254 | 6/20 | 0.48 |
| ▸ | MMP7 | P09237 | 6/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931203 | 0.86 | CAPN2 (0.68) | CAPN2MMP1MMP2MMP3MMP7 | |
| SCHEMBL930000 | 0.81 | CAPN2 (0.54) | CAPN2MMP1MMP2MMP3MMP7 | |
| SCHEMBL15869944 | 0.79 | CAPN2 (0.52) | CAPN2MMP1MMP2MMP3MMP7 | |
| SCHEMBL8209264 | 0.70 | CAPN2 (1.00) | CAPN2CPB2 | |
| SCHEMBL8203817 | 0.69 | CAPN2 (0.98) | CAPN2MMP1MMP2MMP3MMP7 | |
| SCHEMBL931991 | 0.66 | CAPN2 (0.77) | CAPN2MMP1MMP2MMP3MMP7 | |
| SCHEMBL8206132 | 0.66 | CAPN2 (0.82) | CAPN2MMP1MMP2MMP3MMP7 | |
| SCHEMBL931593 | 0.65 | CAPN2 (0.57) | CAPN2MMP1MMP2MMP3MMP7 | |
| SCHEMBL12943169 | 0.65 | CAPN2 (0.56) | CAPN2MMP1MMP2MMP3MMP7 | |
| SCHEMBL12943215 | 0.65 | CAPN2 (0.54) | CAPN2MMP1MMP2MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008048121-A2 | MACROCYCLIC CYSTEINE PROTEASE INHIBITORS AND COMPOSITIONS THEREOF | LINCOLN UNIVERSITY (NZ) | 2008-04-24 | — | — | WO | disclosed |