Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | CASR | P41180 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | MLNR | O43193 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.64 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.64 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.64 |
| ▸ | HRH1 | P35367 | 1/20 | 0.64 |
| ▸ | MC3R | P41968 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226247 | 1.00 | HTR2C (0.64) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL9989657 | 0.90 | CASR (0.69) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL16575625 | 0.90 | CASR (0.69) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL7905227 | 0.89 | CASR (0.64) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL28127001 | 0.88 | CASR (0.63) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL28127003 | 0.88 | CASR (0.63) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL7912988 | 0.88 | HTR2C (0.63) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL10123767 | 0.87 | CASR (0.65) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL10108626 | 0.87 | CASR (0.62) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 | |
| SCHEMBL20307877 | 0.86 | HTR2C (0.64) | HTR2CADRA2CSLC6A2SLC6A4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722732-B2 | Oligomer-calcimimetic conjugates and related compounds | NEKTAR THERAPEUTICS (US) | 2014-05-13 | — | — | US | disclosed |
| WO-2008097546-A2 | COMPOUNDS THAT INHIBIT CHOLINESTERASE | COLUCID PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |