Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.39 |
| ▸ | FDPS | P14324 | 9/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416568 | 1.00 | TSHR (0.44) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL14150218 | 0.92 | TSHR (0.39) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL1110046 | 0.90 | TSHR (0.40) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL10935422 | 0.86 | TSHR (0.35) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL28995684 | 0.82 | TSHR (0.35) | TSHRTHRBFDPS | |
| SCHEMBL19231156 | 0.82 | TSHR (0.35) | TSHRTHRBFDPS | |
| SCHEMBL8686237 | 0.82 | TSHR (0.57) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL10519632 | 0.82 | TSHR (0.57) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Tridecane SCHEMBL8588770 | 0.82 | TSHR (0.57) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL8685336 | 0.82 | TSHR (0.57) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153322-A | Methods for making fluorinated surface modifying agents, methods of using same and products made using same | HOUSTON, UNIVERSITY OF | 2000-11-28 | — | — | US | disclosed |
| WO-1998040169-A1 | METHODS FOR MAKING FLUORINATED SURFACE MODIFYING AGENTS, METHODS OF USING SAME AND PRODUCTS MADE USING SAME | THE UNIVERSITY OF HOUSTON (US) | 1998-09-17 | — | — | WO | disclosed |