SCHEMBL8204015

SCHEMBL8204015

C[C@@H]1CCCC(C)(C)[C@H]1C=O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
EPHX1 P07099 1/20 0.30
TRPA1 O75762 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL958781 1.00 CA1 (0.31) CA1CA2CA4EPHX1TRPA1
SCHEMBL4608681 1.00 CA1 (0.31) CA1CA2CA4EPHX1TRPA1
SCHEMBL20930020 1.00 CA1 (0.31) CA1CA2CA4EPHX1TRPA1
SCHEMBL1276250 1.00 CA1 (0.31) CA1CA2CA4EPHX1TRPA1
SCHEMBL958827 1.00 CA1 (0.31) CA1CA2CA4EPHX1TRPA1
SCHEMBL20930152 1.00 CA1 (0.31) CA1CA2CA4EPHX1TRPA1
SCHEMBL696325 0.86 CYP1A2 (0.33)
SCHEMBL9240986 0.82
SCHEMBL7941765 0.82
SCHEMBL9240998 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6054426-A Optically active aliphatic alcohols and their use as perfuming ingredients FIRMENICH SA (CH) 2000-04-25 US disclosed
EP-0449034-B1 Cyclic ketones, method for their preparation and their application in perfumery FIRMENICH & CIE (CH) 1994-12-28 EP disclosed
EP-0457022-B1 Optically active aliphatic alcohols and their application as perfume ingredients FIRMENICH & CIE (CH) 1994-08-03 EP disclosed
US-5288702-A Floral or fruit-like odor TAKASAGO INTERNATIONAL CORPORATION (JP) 1994-02-22 US disclosed
US-5118865-A CYCLIC KETONES AND THEIR USE AS PERFUMING INGREDIENTS FIRMENICH SA (CH) 1992-06-02 US disclosed
EP-0457022-A1 Optically active aliphatic alcohols and their application as perfume ingredients FIRMENICH SA (CH) 1991-11-21 EP disclosed
EP-0449034-A1 Cyclic ketones, method for their preparation and their application in perfumery FIRMENICH SA (CH) 1991-10-02 EP disclosed