Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12811747 | 1.00 | CYP3A4 (0.44) | CYP3A4 | |
| SCHEMBL8161389 | 0.90 | CMA1 (0.47) | — | |
| SCHEMBL8140310 | 0.89 | — | — | |
| SCHEMBL19312042 | 0.89 | CYP3A4 (0.44) | CYP3A4 | |
| SCHEMBL8388271 | 0.89 | CYP3A4 (0.41) | CYP3A4 | |
| SCHEMBL12336674 | 0.88 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL8130769 | 0.87 | — | — | |
| SCHEMBL8139992 | 0.87 | — | — | |
| SCHEMBL8126617 | 0.87 | — | — | |
| SCHEMBL8137060 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505963-B9 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-21 | — | — | EP | disclosed |
| EP-1505963-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-04-20 | — | — | EP | disclosed |
| WO-2008021733-A2 | TETRAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |