Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.80 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.80 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12478490 | 0.91 | CYP2A6 (0.76) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL13750026 | 0.90 | CYP2C9 (0.74) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL3604362 | 0.89 | CYP2A6 (1.00) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL13527253 | 0.89 | CYP2C9 (0.72) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL1132959 | 0.85 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL5017549 | 0.85 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL5017551 | 0.85 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL5016762 | 0.85 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL5493639 | 0.85 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL5015514 | 0.85 | CYP2A6 (0.70) | CYP2A6CYP2C19CYP3A4CYP2C9CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044208-A1 | ERYTHROMYCIN DERIVATIVES | Pfizer Products Inc. (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999035157-A1 | NOVEL ERYTHROMYCIN DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-07-15 | — | — | WO | claimed |
| EP-3250585-B1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | YEDA RES & DEV (IL) | 2019-08-14 | — | — | EP | disclosed |
| US-9139609-B2 | C-4″ position substituted macrolide derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MRPL21, MRPS34, MRPL37 | CYP2A6 884/4885CYP2C19 508/4885CYP3A4 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.