Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | TP53 | P04637 | 5/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.45 |
| ▸ | GPX4 | P36969 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858355 | 0.88 | TP53 (0.74) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL9214429 | 0.87 | NR1I2 (0.85) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL9210625 | 0.86 | TP53 (0.68) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL9212304 | 0.86 | TP53 (0.76) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL11122093 | 0.85 | TP53 (0.71) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL572323 | 0.84 | TP53 (0.65) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL9207005 | 0.83 | TP53 (0.64) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL11264198 | 0.83 | TP53 (0.67) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| SCHEMBL10726553 | 0.83 | TP53 (0.84) | ALDH1A1TP53TDP1CYP3A4NR1I2 | |
| Acetochlor SCHEMBL4053953 | 0.83 | TP53 (1.00) | ALDH1A1TP53TDP1CYP3A4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840548-B1 | SYNERGISTIC HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF | ZENECA LTD (GB) | 2000-01-05 | — | — | EP | disclosed |
| US-4579691-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |