Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13808007 | 0.88 | TP53 (0.67) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13808039 | 0.87 | CNR1 (0.67) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13807982 | 0.79 | CNR1 (0.65) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13807992 | 0.79 | CNR1 (0.67) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL14043554 | 0.79 | CNR1 (0.59) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13808045 | 0.78 | CNR1 (0.68) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13808041 | 0.78 | CNR1 (0.66) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL5057287 | 0.78 | CNR1 (0.62) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13808042 | 0.78 | CNR1 (0.60) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL14512545 | 0.78 | TP53 (0.68) | TP53LMNAPOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118141-A2 | USE OF CANNABINOID MODULATING COMPOUNDS IN COMBINATION WITH OTHER THERAPEUTIC COMPOUNDS FOR ADJUNCTIVE THERAPY | ACADIA PHARMACEUTICALS INC. (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008048648-A2 | CB1-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-04-24 | — | — | WO | disclosed |