Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047649 | 0.92 | DPP4 (0.53) | DPP4KCNH2CHRM1 | |
| SCHEMBL8214761 | 0.90 | DPP4 (0.43) | DPP4KCNH2CHRM1 | |
| SCHEMBL8211822 | 0.90 | DPP4 (0.45) | DPP4KCNH2CHRM1 | |
| SCHEMBL8217368 | 0.90 | DPP4 (0.44) | DPP4KCNH2CHRM1 | |
| SCHEMBL8214909 | 0.90 | DPP4 (0.44) | DPP4KCNH2CHRM1 | |
| SCHEMBL8212919 | 0.87 | DPP4 (0.45) | DPP4KCNH2CHRM1 | |
| SCHEMBL8212755 | 0.87 | DPP4 (0.50) | DPP4KCNH2CHRM1 | |
| SCHEMBL8214979 | 0.85 | DPP4 (0.44) | DPP4KCNH2CHRM1 | |
| SCHEMBL8219926 | 0.85 | DPP4 (0.43) | DPP4KCNH2CHRM1 | |
| SCHEMBL8214758 | 0.83 | DPP4 (0.44) | DPP4KCNH2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017670-A1 | PYRROLO [3, 2 -D] PYRIMIDINES AS DPP-IV INHIBITORS FOR THE TREATMENT OF DIABETES MELLITUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-14 | — | — | WO | disclosed |