Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999632 | 0.90 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL13038489 | 0.89 | EDNRA (0.93) | EDNRAEDNRB | |
| SCHEMBL8203979 | 0.89 | EDNRA (0.93) | EDNRAEDNRB | |
| SCHEMBL8206788 | 0.88 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL7538123 | 0.88 | EDNRA (0.88) | EDNRAEDNRB | |
| SCHEMBL8226993 | 0.87 | EDNRA (0.74) | EDNRAEDNRB | |
| SCHEMBL7810955 | 0.87 | EDNRA (0.86) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL1028671 | 0.86 | EDNRA (1.00) | EDNRAEDNRB | |
| Enrasentan SCHEMBL1649828 | 0.86 | EDNRA (1.00) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL4197810 | 0.86 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087389-A | TREATING CARDIOVASCULAR AND RENAL DISEASES INCLUDING HYPERTENSION, ACUTE AND CHRONIC RENAL FAILURE, CYCLOSPORINE INDUCED NEPHROTOXICITY, STROKE, CEREBROVASCULAR VASOSPASM, MYOCARDIAL ISCHEMIA, ANGINA, HEART FAILURE, ATHEROSCLEROSIS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-11 | — | — | US | disclosed |