Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868959 | 0.90 | TSHR (0.41) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL7868028 | 0.80 | TSHR (0.45) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL7866273 | 0.76 | TSHR (0.46) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL7868010 | 0.76 | TSHR (0.46) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL9745135 | 0.75 | TSHR (0.52) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL6662257 | 0.71 | TSHR (0.50) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL6200579 | 0.70 | TSHR (0.53) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL3080867 | 0.70 | TSHR (0.53) | TSHRHPGDALDH1A1ATMHCAR2 | |
| SCHEMBL28268101 | 0.69 | TSHR (0.62) | TSHRALDH1A1HCAR2 | |
| SCHEMBL9745996 | 0.69 | TSHR (0.49) | TSHRHPGDALDH1A1ATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147251-A | PREPARATION OF DERIVATIVES OF HALO-BUT-2-ENOIC ACIDS AND ESTERS HIGH IN 2-ENE CONTENT; CATALYST PROMOTERS IN ETHYLENE POLYMERIZATION AND COPOLYMERIZATION | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-11-14 | — | — | US | disclosed |