Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 2/20 | 0.80 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.80 |
| ▸ | STS | P08842 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | ESR1 | P03372 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | PGR | P06401 | 2/20 | 0.70 |
| ▸ | AR | P10275 | 2/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | ATM | Q13315 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205333 | 1.00 | ABCC4 (0.80) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL8931605 | 0.93 | ABCC1 (0.69) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL8621864 | 0.89 | ABCC4 (0.75) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL232796 | 0.89 | ABCC4 (1.00) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL30471686 | 0.89 | ABCC4 (1.00) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL29392632 | 0.89 | ABCC4 (1.00) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL232797 | 0.89 | ABCC4 (1.00) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL4966962 | 0.88 | KDM4E (1.00) | ABCC4ABCC1STSKDM4ELMNA | |
| E2Mate SCHEMBL5165269 | 0.88 | STS (1.00) | ABCC4ABCC1STSKDM4ELMNA | |
| SCHEMBL20634998 | 0.88 | ABCC4 (0.83) | ABCC4ABCC1STSKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | claimed |
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | disclosed |