SCHEMBL8205574

SCHEMBL8205574

CCC(C)(C)c1ccc(OC(=O)c2ccccc2O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.67
HPGD P15428 4/20 0.59
HSD17B10 Q99714 4/20 0.59
ALOX15 P16050 2/20 0.59
MAPT P10636 6/20 0.51
NPSR1 Q6W5P4 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.47
TSHR P16473 2/20 0.46
LMNA P02545 2/20 0.46
RAB9A P51151 3/20 0.45
POLB P06746 2/20 0.45
NPC1 O15118 2/20 0.45
CYP2C9 P11712 2/20 0.45
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41
CASP3 P42574 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698506 0.87 HPGD (0.58) TDP1HPGDHSD17B10ALOX15MAPT
SCHEMBL432391 0.85 HPGD (0.52) TDP1HPGDHSD17B10ALOX15MAPT
SCHEMBL11575738 0.85 TDP1 (0.55) TDP1HPGDHSD17B10ALOX15MAPT
SCHEMBL29645273 0.85 MAPT (0.68) TDP1HPGDHSD17B10ALOX15MAPT
SCHEMBL77201 0.85 MAPT (0.68) TDP1HPGDHSD17B10ALOX15MAPT
SCHEMBL3830500 0.85 HPGD (0.67) TDP1HPGDHSD17B10ALOX15MAPT
SCHEMBL28320193 0.84 MAPT (0.67) TDP1HPGDHSD17B10ALOX15MAPT
SCHEMBL526044 0.84 HPGD (0.65) TDP1HPGDHSD17B10ALOX15MAPT
SCHEMBL9769806 0.83 TDP1 (0.60) TDP1HPGDHSD17B10MAPTNPSR1
Phenyl Salicylate SCHEMBL6429855 0.82 HSD17B10 (0.73) TDP1HPGDHSD17B10ALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US claimed
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7534539-B2 Electrophotographic photoreceptor and image forming apparatus having the same SHARP KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 US disclosed
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US disclosed