Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 12/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858129 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL7407403 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL8209979 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL8205854 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL10859141 | 0.90 | KDM4E (0.52) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL10859071 | 0.90 | KDM4E (0.52) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL10859022 | 0.90 | KDM4E (0.52) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL10859448 | 0.88 | KDM4E (0.70) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL10859537 | 0.88 | KDM4E (0.70) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 | |
| SCHEMBL10859498 | 0.88 | KDM4E (0.70) | KDM4EALDH1A1NPSR1HSD17B10CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596803-A | Treating myocardial infarction | NIPPON CHEMIPHAR CO., LTD. (JP) | 1986-06-24 | — | — | US | claimed |
| US-6054437-A | Method for inducing death of neoplastic cells using piperazine derivatives | HITACHI CHEMICAL RESEARCH CENTER, INC. (US) | 2000-04-25 | — | — | US | disclosed |
| US-4596803-A | Treating myocardial infarction | NIPPON CHEMIPHAR CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4507297-A | MYOCARDIAL INFARCTION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-03-26 | — | — | US | disclosed |