Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH1 | P20839 | 17/20 | 0.79 |
| ▸ | IMPDH2 | P12268 | 14/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206728 | 1.00 | IMPDH1 (0.79) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL1152849 | 1.00 | IMPDH1 (0.79) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL8212537 | 0.97 | IMPDH1 (0.83) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL8206043 | 0.97 | IMPDH1 (0.83) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL1152729 | 0.97 | IMPDH1 (0.83) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL29463176 | 0.97 | IMPDH1 (0.83) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL1153350 | 0.87 | IMPDH1 (0.68) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL1152538 | 0.86 | IMPDH1 (0.64) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL8544680 | 0.84 | IMPDH1 (0.58) | IMPDH1IMPDH2KDM4EALDH1A1LMNA | |
| SCHEMBL1153706 | 0.84 | IMPDH1 (0.58) | IMPDH1IMPDH2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745073-B1 | 5-SUBSTITUTED DERIVATIVES OF MYCOPHENOLIC ACID | SYNTEX INC (US) | 2000-07-12 | — | — | EP | disclosed |
| US-5633279-A | 5-substituted derivatives of mycophenolic acid | SYNTEX (U.S.A.) INC. (US) | 1997-05-27 | — | — | US | disclosed |
| US-5493030-A | CHEMICAL INTERMEDIATES | SYNTEX (U.S.A.) INC. (US) | 1996-02-20 | — | — | US | disclosed |