Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007880 | 1.00 | PDE8B (0.30) | PDE8B | |
| SCHEMBL3179381 | 0.88 | — | — | |
| SCHEMBL26127325 | 0.83 | ANPEP (0.32) | — | |
| SCHEMBL2325319 | 0.83 | ANPEP (0.32) | — | |
| SCHEMBL8207017 | 0.83 | ANPEP (0.32) | — | |
| SCHEMBL499587 | 0.83 | ANPEP (0.32) | — | |
| SCHEMBL499586 | 0.83 | ANPEP (0.32) | — | |
| SCHEMBL13503041 | 0.80 | — | — | |
| SCHEMBL18542421 | 0.79 | — | — | |
| SCHEMBL15107625 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074108-B1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2012-11-21 | — | — | EP | disclosed |
| WO-2008036247-A1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | disclosed |