Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.71 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889995 | 0.88 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3HTR6NOS3 | |
| SCHEMBL2889993 | 0.88 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3HTR6NOS3 | |
| Hydrochloric Acid SCHEMBL2891904 | 0.87 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC6A3HTR6NOS3 | |
| SCHEMBL1020818 | 0.83 | SLC6A2 (0.69) | SLC6A4SLC6A2SLC6A3HTR6NOS3 | |
| SCHEMBL1020817 | 0.83 | SLC6A2 (0.69) | SLC6A4SLC6A2SLC6A3HTR6NOS3 | |
| SCHEMBL5829586 | 0.83 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3HTR6NOS3 | |
| SCHEMBL5829683 | 0.83 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3HTR6NOS3 | |
| Hydrochloric Acid SCHEMBL1023640 | 0.82 | SLC6A2 (0.68) | SLC6A4SLC6A2SLC6A3HTR6NOS3 | |
| SCHEMBL6491789 | 0.81 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3HTR6HTR1A | |
| SCHEMBL6491784 | 0.81 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3HTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984965-A1 | 8-AZABICYCLO(3,2,1)OCT-2-ENE AND OCTANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACH RECEPTORS | NEUROSEARCH A/S (DK) | 2000-03-15 | — | — | EP | claimed |
| WO-1998054181-A1 | 8-AZABICYCLO(3,2,1)OCT-2-ENE AND OCTANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACH RECEPTORS | NEUROSEARCH A/S (DK) | 1998-12-03 | — | — | WO | claimed |