Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937658 | 1.00 | USP2 (0.61) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL13189917 | 0.94 | USP2 (0.52) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL3431986 | 0.80 | USP2 (0.57) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL9549501 | 0.80 | USP2 (0.57) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL1080339 | 0.79 | USP2 (0.55) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL9818719 | 0.78 | PDE4A (0.58) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL28085169 | 0.78 | PDE4A (0.58) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL2937201 | 0.78 | PDE4A (0.58) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL13189918 | 0.78 | USP2 (0.32) | USP2SLCO1B1 | |
| SCHEMBL18177455 | 0.77 | PDE4A (0.56) | USP2SLCO1B1LMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000007602-A1 | COMPOUNDS FOR ALTERING CELL SURFACE SIALIC ACIDS AND METHODS OF USE THEREFOR | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2000-02-17 | — | — | WO | disclosed |