SCHEMBL8208573

SCHEMBL8208573

COCC1CCC(CCc2ccc(-c3ccc(C4CCC(CCCF)CC4)c(F)c3)cc2)CC1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 11/20 0.37
KCNH2 Q12809 1/20 0.33
DGAT1 O75907 1/20 0.33
MAOB P27338 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8214985 0.95 OPRL1 (0.37) OPRL1DGAT1MAOB
SCHEMBL8215857 0.92 OPRL1 (0.41) OPRL1DGAT1
SCHEMBL8216127 0.89 OPRL1 (0.38) OPRL1DGAT1
SCHEMBL8218502 0.89 OPRL1 (0.40) OPRL1DGAT1
SCHEMBL8219141 0.89 OPRL1 (0.38) OPRL1DGAT1
SCHEMBL8217740 0.86 RARB (0.38) OPRL1DGAT1
SCHEMBL8217745 0.86 RARB (0.38) OPRL1DGAT1
SCHEMBL8208432 0.82 OPRL1 (0.41) OPRL1DGAT1
SCHEMBL8215975 0.81 OPRL1 (0.38) OPRL1DGAT1
SCHEMBL8216702 0.81 OPRL1 (0.35) OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117361-A FOUR RING COMPOUND HAVING AN ALKYL GROUP SUBSTITUTED WITH ONE OR MORE ETHERS, AND A HALOGEN ATOM SUBSTITUTED BENZENE RING; BROAD TEMPERATURE RANGE OF NEMATIC PHASE, HIGHER MISCIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS, AND CHEMICAL STABILITY CHISSO CORP. (JP) 2000-09-12 US disclosed
EP-0891961-A1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED 1,4-PHENYLENE SKELETONS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORPORATION (JP) 1999-01-20 EP disclosed