Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.65 |
| ▸ | STAT3 | P40763 | 1/20 | 0.63 |
| ▸ | NAAA | Q02083 | 5/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159324 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL31519438 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL6158388 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL8219400 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL8209628 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL8211443 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL8220018 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL7413739 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL8219403 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A | |
| SCHEMBL8211445 | 1.00 | IL6ST (0.65) | IL6STSTAT3NAAAPLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621270-B1 | Piperazine derivatives as collagenase inhibitors | SANKYO CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5643908-A | ANGIOGENESIS INHIBITOR, ANTITUMOR | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0621270-A1 | COLLAGENASE INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1994-10-26 | — | — | EP | disclosed |