Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.81 |
| ▸ | PDE11A | Q9HCR9 | 8/20 | 0.81 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12163017 | 0.90 | PDE4B (0.66) | PDE4BPDE11APDE10A | |
| SCHEMBL8272980 | 0.89 | PDE4B (1.00) | PDE4BPDE11APDE10A | |
| SCHEMBL8276489 | 0.88 | PDE4B (0.64) | PDE4BPDE11APDE10A | |
| SCHEMBL13918607 | 0.87 | PDE4B (0.74) | PDE4BPDE11APDE10A | |
| SCHEMBL8275050 | 0.87 | PDE4B (1.00) | PDE4BPDE11APDE10A | |
| SCHEMBL8275243 | 0.87 | PDE4B (0.83) | PDE4BPDE11APDE10A | |
| SCHEMBL12396153 | 0.86 | PDE4B (0.68) | PDE4BPDE11APDE10A | |
| SCHEMBL8273037 | 0.86 | PDE4B (0.61) | PDE4BPDE11APDE10A | |
| SCHEMBL13920551 | 0.86 | PDE4B (0.61) | PDE4BPDE11APDE10A | |
| SCHEMBL12923214 | 0.86 | PDE4B (0.66) | PDE4BPDE11APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385050-A1 | A process for preparing a substituted oxazole | Schering Corporation (US) | 2011-11-09 | — | — | EP | disclosed |
| EP-2385051-A1 | Process for making a substituted oxazole | Schering Corporation (US) | 2011-11-09 | — | — | EP | disclosed |
| WO-2008021235-A2 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 2-(QUINOLIN-5-YL)-4,5 DISUBSTITUTED-AZOLE DERIVATIVES | SCHERING CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |