SCHEMBL8209935

SCHEMBL8209935

CNC(=O)/C(=N/OC)c1ccccc1COC/C=N/OC(Cc1ccccc1)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.41
MIF P14174 2/20 0.38
PPARG P37231 3/20 0.36
PPARA Q07869 3/20 0.36
CAPN1 P07384 2/20 0.33
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8209643 0.92 HIF1A (0.43) HIF1AMIFPPARGPPARACAPN1
SCHEMBL8210930 0.92 HIF1A (0.43) HIF1AMIFPPARGPPARACAPN1
SCHEMBL8201445 0.79 MIF (0.38) MIFPPARGPPARACAPN1KMT2A
SCHEMBL8214102 0.76 HIF1A (0.40) HIF1A
SCHEMBL8211670 0.76 HIF1A (0.39) HIF1A
SCHEMBL8259072 0.76 HIF1A (0.39) HIF1A
SCHEMBL8504225 0.72 HIF1A (0.49) HIF1APPARGPPARA
SCHEMBL8368526 0.71 HIF1A (0.49) HIF1AMEN1KMT2A
SCHEMBL8368529 0.71 HIF1A (0.49) HIF1AMEN1KMT2A
SCHEMBL8954797 0.71 HIF1A (0.49) HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1021399-A2 FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS AVENTIS CROPSCIENCE S.A. (FR) 2000-07-26 EP disclosed
WO-1998015512-A2 FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS RHONE POULENC AGROCHIMIE (FR) 1998-04-16 WO disclosed