Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | NOS1 | P29475 | 2/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24965971 | 0.83 | TAAR1 (0.57) | TAAR1 | |
| SCHEMBL12500551 | 0.81 | TAAR1 (0.65) | TAAR1NOS1NOS3KDM4EALDH1A1 | |
| SCHEMBL10201988 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1 | |
| SCHEMBL21089609 | 0.81 | TAAR1 (0.60) | TAAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22566654 | 0.80 | TAAR1 (0.68) | TAAR1NOS1NOS3KDM4EMEN1 | |
| SCHEMBL14608016 | 0.80 | TAAR1 (0.53) | TAAR1SCN8A | |
| SCHEMBL14566080 | 0.80 | TAAR1 (0.55) | TAAR1KDM4EALDH1A1KMT2A | |
| SCHEMBL7235032 | 0.79 | GAA (0.65) | TAAR1KDM4EMEN1KMT2A | |
| SCHEMBL31114405 | 0.78 | TAAR1 (0.67) | TAAR1NOS1NOS3KDM4E | |
| SCHEMBL2257962 | 0.78 | TAAR1 (0.61) | TAAR1NOS1NOS3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042353-A1 | POTENT AND HIGHLY SELECTIVE HETEROAROMATIC INHIBITORS OF NEURONAL NITRIC OXIDE SYNTHASE | NORTHWESTERN UNIVERSITY (US) | 2008-04-10 | — | — | WO | disclosed |