Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089245 | 0.90 | CTSC (0.33) | CTSCCYP1A2CYP3A4CTSHCYP2D6 | |
| SCHEMBL7136092 | 0.81 | DPP4 (0.49) | DPP4 | |
| SCHEMBL8721584 | 0.77 | DPP7 (0.58) | CTSCCYP1A2CYP3A4CTSHCYP2D6 | |
| SCHEMBL2184463 | 0.75 | CTSC (0.47) | CTSCCYP1A2CYP3A4CTSHCYP2D6 | |
| SCHEMBL4046388 | 0.74 | KDM4E (0.32) | — | |
| SCHEMBL9221199 | 0.72 | CTSC (0.43) | CTSCCTSHCTSKDPP4 | |
| SCHEMBL9797628 | 0.70 | DPP7 (0.50) | CTSCCTSHCTSKDPP4DPP8 | |
| SCHEMBL8991404 | 0.70 | DPP7 (0.50) | CTSCCTSHCTSKDPP4DPP8 | |
| SCHEMBL10724867 | 0.69 | DPP7 (0.40) | CTSCCYP1A2CYP3A4CTSHCYP2D6 | |
| SCHEMBL5045442 | 0.69 | CA1 (0.45) | CYP2D6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103698-A | USEFUL IN TREATING CANCER IN A MAMMAL; IN COMBINATION WITH PACLITAXEL AND TAXOTERE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | claimed |