Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24095980 | 1.00 | CA12 (0.53) | CA12CA2CA1POLBCA9 | |
| SCHEMBL8210490 | 1.00 | CA12 (0.53) | CA12CA2CA1POLBCA9 | |
| Hydrochloric Acid SCHEMBL27498990 | 0.98 | CA12 (0.52) | CA12CA2CA1POLBCA9 | |
| Hydrochloric Acid SCHEMBL3367304 | 0.98 | CA12 (0.52) | CA12CA2CA1POLBCA9 | |
| SCHEMBL11710494 | 0.89 | POLB (0.54) | CA12CA2POLBCA9KMT2A | |
| SCHEMBL24322367 | 0.89 | POLB (0.54) | CA12CA2POLBCA9KMT2A | |
| SCHEMBL10742096 | 0.87 | KMT2A (0.58) | KMT2AMMP1MMP2MMP3 | |
| SCHEMBL24096256 | 0.86 | HDAC8 (0.55) | CA12CA2CA1CYP2D6CYP2C19 | |
| Bromide SCHEMBL10745588 | 0.86 | KMT2A (0.57) | KMT2AMMP1MMP2MMP3 | |
| Bromide SCHEMBL10745592 | 0.86 | KMT2A (0.57) | KMT2AMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987274-A1 | Factor VIIa Inhibitors | Hoechst Marion Roussel Deutschland GmbH (DE) | 2000-03-22 | — | — | EP | disclosed |