Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 14/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202468 | 0.92 | CACNA1H (0.68) | CACNA1HTRPV1 | |
| SCHEMBL14263418 | 0.91 | CACNA1H (0.81) | CACNA1HTRPV1 | |
| SCHEMBL8210396 | 0.90 | TRPV1 (0.66) | CACNA1HTRPV1CA12CA1CA2 | |
| SCHEMBL8208298 | 0.90 | CACNA1H (0.58) | CACNA1HTRPV1CA12CA1CA2 | |
| SCHEMBL8202488 | 0.87 | CACNA1H (0.75) | CACNA1HTRPV1 | |
| SCHEMBL8210596 | 0.85 | CACNA1H (0.55) | CACNA1HTRPV1 | |
| SCHEMBL8210802 | 0.85 | CACNA1H (0.57) | CACNA1HTRPV1 | |
| SCHEMBL8209771 | 0.85 | CACNA1H (0.57) | CACNA1HTRPV1 | |
| SCHEMBL8210273 | 0.85 | TRPV1 (0.54) | CACNA1HTRPV1 | |
| SCHEMBL8201876 | 0.84 | CACNA1H (0.51) | CACNA1HTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033465-A1 | AZETIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |