Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217092 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8217091 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8212022 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8211296 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8211994 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8212020 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8211299 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8209572 | 0.98 | GRIK1 (0.44) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8212027 | 0.98 | GRIK1 (0.44) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8209570 | 0.98 | GRIK1 (0.44) | GRIK1GRIK2SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621270-B1 | Piperazine derivatives as collagenase inhibitors | SANKYO CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5643908-A | ANGIOGENESIS INHIBITOR, ANTITUMOR | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0621270-A1 | COLLAGENASE INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1994-10-26 | — | — | EP | disclosed |