Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058677 | 0.83 | CNR1 (0.66) | MAPTCNR1RXRASMN1; SMN2NPSR1 | |
| SCHEMBL14205655 | 0.80 | CNR1 (0.54) | MAPTCNR1RXRALMNAHTT | |
| SCHEMBL13807777 | 0.77 | CNR1 (0.51) | MAPTCNR1RXRALMNAHTT | |
| SCHEMBL13807947 | 0.77 | CNR1 (0.41) | POLBMAPTCNR1RXRALMNA | |
| SCHEMBL13807944 | 0.77 | CNR1 (0.46) | POLBMAPTCNR1RXRATP53 | |
| SCHEMBL14043580 | 0.76 | TP53 (0.58) | POLBMAPTCNR1LMNAHTT | |
| SCHEMBL14043678 | 0.74 | CNR1 (0.47) | MAPTCNR1RXRALMNAHTT | |
| SCHEMBL13808180 | 0.71 | CNR1 (0.44) | MAPTCNR1RXRALMNAHTT | |
| SCHEMBL8211812 | 0.69 | CNR1 (0.62) | POLBMAPTCNR1LMNAHTT | |
| SCHEMBL8213532 | 0.69 | MAPT (0.39) | POLBMAPTCNR1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008048648-A2 | CB1-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-04-24 | — | — | WO | disclosed |