Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RBP1 | P09455 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221694 | 0.96 | MEN1 (0.52) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8220541 | 0.92 | MEN1 (0.47) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8221632 | 0.92 | MEN1 (0.47) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8221699 | 0.91 | MEN1 (0.47) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8225204 | 0.91 | MEN1 (0.46) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8224011 | 0.90 | MEN1 (0.45) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8221173 | 0.88 | KMT2A (0.62) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8223584 | 0.87 | MEN1 (0.42) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8222201 | 0.84 | KMT2A (0.65) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL8224398 | 0.84 | MEN1 (0.56) | KMT2AMEN1HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |