Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.49 |
| ▸ | FAP | Q12884 | 3/20 | 0.49 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219154 | 0.99 | DPP4 (0.57) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL8217349 | 0.99 | DPP4 (0.58) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL8219922 | 0.94 | DPP4 (0.56) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL8217576 | 0.92 | DPP4 (0.60) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL8213182 | 0.92 | DPP4 (0.60) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL12047764 | 0.92 | DPP4 (0.69) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL12047777 | 0.91 | DPP4 (0.68) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL12047749 | 0.90 | DPP4 (0.69) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL8213186 | 0.90 | DPP4 (0.58) | DPP4KCNH2FAPPOU2F2ADORA3 | |
| SCHEMBL8213489 | 0.90 | DPP4 (0.58) | DPP4KCNH2FAPPOU2F2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017670-A1 | PYRROLO [3, 2 -D] PYRIMIDINES AS DPP-IV INHIBITORS FOR THE TREATMENT OF DIABETES MELLITUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-14 | — | — | WO | disclosed |