Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076413 | 0.90 | GRM2 (0.41) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL13140443 | 0.88 | GRM2 (0.43) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL3075697 | 0.88 | GRM2 (0.40) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL3067237 | 0.88 | GRM2 (0.40) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL3070704 | 0.86 | GRM2 (0.41) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL3073001 | 0.83 | GRM2 (0.44) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL8213419 | 0.81 | GRM2 (0.44) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL3068777 | 0.81 | GRM2 (0.46) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL3073111 | 0.80 | GRM2 (0.50) | GRM2GRIN1GRIN2BTACR2TACR1 | |
| SCHEMBL3074256 | 0.79 | GRM2 (0.55) | GRM2GRIN1GRIN2BTACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008032191-A2 | SPIRO-OXAZOLIDINONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (US) | 2008-03-20 | — | — | WO | disclosed |