Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.69 |
| ▸ | FAP | Q12884 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047545 | 0.92 | DPP4 (0.70) | DPP4KCNH2FAP | |
| SCHEMBL8214971 | 0.86 | DPP4 (0.62) | DPP4KCNH2FAP | |
| SCHEMBL8214983 | 0.86 | DPP4 (0.82) | DPP4KCNH2FAP | |
| SCHEMBL8215864 | 0.85 | DPP4 (0.52) | DPP4KCNH2FAP | |
| SCHEMBL8214180 | 0.84 | DPP4 (0.51) | DPP4KCNH2FAP | |
| SCHEMBL8215002 | 0.84 | DPP4 (0.51) | DPP4KCNH2FAP | |
| SCHEMBL8204977 | 0.83 | DPP4 (0.63) | DPP4KCNH2FAP | |
| SCHEMBL8217212 | 0.83 | DPP4 (0.67) | DPP4KCNH2FAP | |
| SCHEMBL8215562 | 0.83 | DPP4 (0.51) | DPP4KCNH2FAP | |
| SCHEMBL8222775 | 0.83 | DPP4 (0.50) | DPP4KCNH2FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017670-A1 | PYRROLO [3, 2 -D] PYRIMIDINES AS DPP-IV INHIBITORS FOR THE TREATMENT OF DIABETES MELLITUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-14 | — | — | WO | disclosed |