Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600904 | 0.89 | PIK3CA (0.58) | MTORPIK3CAPIK3CD | |
| SCHEMBL3602032 | 0.80 | MTOR (0.84) | MTORPIK3CAPIK3CGPIK3CD | |
| SCHEMBL3600580 | 0.79 | PIK3CA (0.59) | MTORPIK3CAPIK3CGPIK3CD | |
| SCHEMBL3722063 | 0.76 | PIK3CA (0.61) | MTORPIK3CAPIK3CG | |
| SCHEMBL3597059 | 0.75 | PIK3CA (0.63) | MTORPIK3CAPIK3CGPIK3CD | |
| SCHEMBL3590940 | 0.75 | PIK3CA (0.58) | MTORPIK3CAPIK3CD | |
| SCHEMBL11898091 | 0.75 | PIK3CA (0.60) | MTORPIK3CAPIK3CGPIK3CD | |
| SCHEMBL3593045 | 0.75 | PIK3CA (0.62) | MTORPIK3CAPIK3CGPIK3CD | |
| SCHEMBL8205955 | 0.74 | MTOR (0.64) | MTORPIK3CAPIK3CGPIK3CD | |
| SCHEMBL8218959 | 0.74 | PIK3CA (0.59) | MTORPIK3CAPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023159-A1 | MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-02-28 | — | — | WO | disclosed |