Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 12/20 | 0.42 |
| ▸ | HTR1A | P08908 | 10/20 | 0.42 |
| ▸ | DRD2 | P14416 | 10/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223212 | 0.96 | MEN1 (0.51) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8212358 | 0.91 | KMT2A (0.60) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8220164 | 0.89 | MEN1 (0.54) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8214020 | 0.89 | KMT2A (0.54) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8221259 | 0.88 | MEN1 (0.54) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8224487 | 0.88 | KMT2A (0.54) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8222201 | 0.88 | KMT2A (0.65) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8220136 | 0.88 | MEN1 (0.53) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8220788 | 0.87 | KMT2A (0.64) | MEN1KMT2AALDH1A1DRD4HTR1A | |
| SCHEMBL8223584 | 0.84 | MEN1 (0.42) | MEN1KMT2AALDH1A1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |