⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768643 | 0.60 | — | — | |
| SCHEMBL639659 | 0.60 | — | — | |
| SCHEMBL4852319 | 0.55 | — | — | |
| SCHEMBL12384340 | 0.55 | — | — | |
| SCHEMBL3672524 | 0.55 | — | — | |
| SCHEMBL247948 | 0.55 | — | — | |
| SCHEMBL2079444 | 0.55 | — | — | |
| SCHEMBL38742 | 0.55 | — | — | |
| SCHEMBL26628 | 0.55 | — | — | |
| SCHEMBL443741 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820840-A1 | AN IMPROVED PROCESS FOR DIASTER-EOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | Piramal Pharma Limited (IN) | 2021-05-19 | — | — | EP | claimed |
| WO-2020012403-A1 | AN IMPROVED PROCESS FOR DIASTER-EOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | Piramal Enterprises Limited (IN) | 2020-01-16 | — | — | WO | claimed |
| EP-3820840-A1 | AN IMPROVED PROCESS FOR DIASTER-EOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | Piramal Pharma Limited (IN) | 2021-05-19 | — | — | EP | disclosed |
| EP-3820840-A1 | AN IMPROVED PROCESS FOR DIASTER-EOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | Piramal Pharma Limited (IN) | 2021-05-19 | — | — | EP | disclosed |
| US-10888853-B2 | Cinchonium betaine catalysts and methods of using same | BRANDEIS UNIVERSITY (US) | 2021-01-12 | — | — | US | disclosed |
| US-10836761-B2 | Cinchonine-derived catalysts and methods of using same | BRANDEIS UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20200147593-A1 | Cinchonium betaine catalysts and methods of using same | BRANDEIS UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
| US-10610857-B2 | Cinchonium betaine catalysts and methods of using same | BRANDEIS UNIVERSITY (US) | 2020-04-07 | — | — | US | disclosed |
| US-20200048243-A1 | CINCHONINE-DERIVED CATALYSTS AND METHODS OF USING SAME | BRANDEIS UNIVERSITY (US) | 2020-02-13 | — | — | US | disclosed |
| WO-2020012403-A1 | AN IMPROVED PROCESS FOR DIASTER-EOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | Piramal Enterprises Limited (IN) | 2020-01-16 | — | — | WO | disclosed |
| WO-2020012403-A1 | AN IMPROVED PROCESS FOR DIASTER-EOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | Piramal Enterprises Limited (IN) | 2020-01-16 | — | — | WO | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| WO-2006007586-A1 | ORGANOCATALYSTS AND METHODS OF USE IN CHEMICAL SYNTHESIS | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2006-01-19 | — | — | WO | disclosed |
| US-6617456-B1 | Aminoalkoxy- or hydroxyalkoxy- camptothecin compound that can be bound to a polysaccharide having carboxyl groups via an amino acid or a peptide group; antitumor agents | TANABE SEIYAKU CO., LTD. (JP) | 2003-09-09 | — | — | US | disclosed |
| US-6512118-B1 | Pharmaceutically acceptable salt thereof show excellent antitumor activities against various tumors, especially they show excellent therapeutic effects on solid tumors such as pulmonary cancer, uterine cancer, ovarian cancer, breast | TANABE SEIYAKU CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-0781781-B1 | Camptothecin derivatives | TANABE SEIYAKU CO (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-5892043-A | MIXTURE WITH POLYSACCHARIDE AND PEPTIDE; ANTITUMOR AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0781781-A2 | Camptothecin derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |
| US-5594008-A | ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0657451-A2 | Pyrrolidine derivatives inhibitors of leukotriene biosynthesis | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1995-06-14 | — | — | EP | disclosed |