Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211953 | 0.96 | RARB (0.32) | RARBFFAR4OPRL1 | |
| SCHEMBL8216752 | 0.90 | OPRL1 (0.32) | FFAR4OPRL1 | |
| SCHEMBL8214806 | 0.86 | RARB (0.39) | RARBFFAR4RARARARGOPRL1 | |
| SCHEMBL8216097 | 0.86 | RARB (0.35) | RARBFFAR4 | |
| SCHEMBL8211949 | 0.83 | OPRL1 (0.35) | RARBFFAR4OPRL1 | |
| SCHEMBL8216702 | 0.83 | OPRL1 (0.35) | RARBFAAHPTGS2FFAR4OPRL1 | |
| SCHEMBL8208571 | 0.82 | SPHK1 (0.33) | — | |
| SCHEMBL19722089 | 0.81 | RARB (0.41) | RARBFFAR4RARARARGOPRL1 | |
| SCHEMBL8267401 | 0.81 | OPRL1 (0.38) | FFAR4OPRL1 | |
| SCHEMBL21321659 | 0.80 | RARB (0.45) | RARBFFAR4RARARARGOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117361-A | FOUR RING COMPOUND HAVING AN ALKYL GROUP SUBSTITUTED WITH ONE OR MORE ETHERS, AND A HALOGEN ATOM SUBSTITUTED BENZENE RING; BROAD TEMPERATURE RANGE OF NEMATIC PHASE, HIGHER MISCIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS, AND CHEMICAL STABILITY | CHISSO CORP. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0891961-A1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED 1,4-PHENYLENE SKELETONS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-20 | — | — | EP | disclosed |