SCHEMBL821493

SCHEMBL821493

[3H]NI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL12352316 0.55
Methylamine SCHEMBL824896 0.55
SCHEMBL12421178 0.55
SCHEMBL416901 0.55
SCHEMBL16689649 0.55
SCHEMBL11890279 0.55
SCHEMBL94465 0.52
SCHEMBL287800 0.52
SCHEMBL3118439 0.52
SCHEMBL5153531 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170275263-A1 Compounds for the treatment of HPV-induced carcinoma ÅBO AKADEMI (FI) 2017-09-28 US disclosed
US-9771359-B1 Substituted oxazole- and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II MEDIFRON DBT INC. (KR) 2017-09-26 US disclosed
US-20170253586-A1 Substituted Oxazole- and Thiazole-Based Carboxamide and Urea Derivatives as Vanilloid Receptor Ligands II MEDIFRON DBT INC. (KR) 2017-09-07 US disclosed
US-9725459-B2 3-oxo-tetrahydro-furo[3,2-B]pyrrol-4(5H)-yl) derivatives I GRUNENTHAL GMBH (DE) 2017-08-08 US disclosed
US-9718823-B2 2, 6-Di-nitrogen-containing substituted purine derivative, and preparation method, pharmaceutical composition and use thereof ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (CN) 2017-08-01 US disclosed
US-9701622-B2 Antibacterial agents ACHAOGEN, INC. (US) 2017-07-11 US disclosed
US-9695166-B2 Pyrazolopyridine pyrazolopyrimidine and related compounds GLOBAL BLOOD THERAPEUTICS, INC. (US) 2017-07-04 US disclosed
US-20170174654-A1 COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN GLOBAL BLOOD THERAPEUTICS, INC. 2017-06-22 US disclosed
US-20170128580-A1 TARGETED THERAPEUTICS TARVEDA THERAPEUTICS, INC. 2017-05-11 US disclosed
US-20170114073-A1 MK2 INHIBITORS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY 2017-04-27 US disclosed
US-20090312304-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2009-12-17 US disclosed
US-20090275593-A1 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors NOVARTIS AG 2009-11-05 US disclosed
US-20090226546-A1 COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS D-HERB LTD. (IL) 2009-09-10 US disclosed
US-20090136473-A1 BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS DECODE GENETICS EHF (IS) 2009-05-28 US disclosed
US-20090137566-A1 Substituted Piperdines as Renin Inhibitors EHARA TAKERU 2009-05-28 US disclosed
US-7438904-B1 High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2008-10-21 US disclosed
US-20080242662-A1 Organic Compounds NIHONYANAGI ATSUKO 2008-10-02 US disclosed
US-20080236770-A1 RAPID FATTY ACID ASSAY FOR USE IN PULP PITCH CONTROL ENZYMATIC DEINKING TECHNOLOGIES, LLC 2008-10-02 US disclosed
US-20080078519-A1 Rapid Fatty Acid Assay for Use in Pulp Pitch Control ENZYMATIC DEINKING TECHNOLOGIES, LLC 2008-04-03 US disclosed
US-20070154572-A1 Compositions derived from portulaca oleracea l. and methods of using same for modulating blood glucose levels D-HERB LTD. (IL) 2007-07-05 US disclosed