Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009451 | 0.88 | GRM5 (0.55) | GRM5ALDH1A1HPGDGAATDP1 | |
| SCHEMBL1008831 | 0.88 | GRM5 (0.46) | GRM5ALDH1A1HPGDLMNAGAA | |
| SCHEMBL8217311 | 0.84 | GRM5 (0.43) | GRM5ALDH1A1LMNAKDM4E | |
| SCHEMBL1011055 | 0.81 | GRM5 (0.47) | GRM5ALDH1A1HPGDLMNAGAA | |
| SCHEMBL1009187 | 0.80 | GRM5 (0.55) | GRM5ALDH1A1HPGDGAATDP1 | |
| SCHEMBL3813925 | 0.77 | DRD1 (0.37) | GRM5GAAKDM4E | |
| SCHEMBL3819224 | 0.77 | GRM5 (0.38) | GRM5ALDH1A1HPGDLMNAGAA | |
| SCHEMBL1010650 | 0.77 | GRM5 (0.48) | GRM5ALDH1A1HPGDLMNA | |
| SCHEMBL15020037 | 0.77 | GRM5 (0.48) | GRM5ALDH1A1HPGDLMNA | |
| SCHEMBL1011624 | 0.77 | GRM5 (0.48) | GRM5ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015269-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-02-07 | — | — | WO | disclosed |