Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763969 | 0.79 | TSHR (0.46) | NPC1RAB9ACA2ALDH1A1MAPT | |
| SCHEMBL27350060 | 0.78 | GFER (0.52) | GFERMAOBMAOACA2ALDH1A1 | |
| SCHEMBL5962 | 0.78 | GFER (0.68) | GFERCYP19A1MAOBMAOACA2 | |
| SCHEMBL16742377 | 0.76 | MAPT (0.49) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL29155827 | 0.75 | GFER (0.65) | GFERCYP19A1MAOBMAOACA2 | |
| SCHEMBL2026345 | 0.74 | TDP1 (0.46) | GFERCYP19A1NPC1RAB9AMAOA | |
| SCHEMBL11935855 | 0.74 | MAPT (0.49) | GFERNPC1RAB9AMAOBMAOA | |
| Ethylamine SCHEMBL27859952 | 0.73 | GFER (0.62) | GFERCYP19A1MAOBMAOACA2 | |
| SCHEMBL1979097 | 0.72 | CYP3A4 (0.37) | GFERRAB9AALDH1A1MAPT | |
| SCHEMBL1696232 | 0.72 | GFER (0.59) | GFERCYP19A1NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019720-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998027427-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |