Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 8/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Aminobenzamide SCHEMBL28759683 | 0.89 | PBRM1 (0.60) | PBRM1MAPTGAAPARP1F2 | |
| 3-Aminobenzamide SCHEMBL27679552 | 0.85 | PBRM1 (0.63) | PBRM1MAPTPARP1F2PLG | |
| 3-Aminobenzamide SCHEMBL16070 | 0.85 | PBRM1 (0.63) | PBRM1MAPTPARP1F2PLG | |
| Anthranilamide SCHEMBL28625886 | 0.83 | MAPT (0.67) | MAPTGAAPARP1TSHRHSD17B10 | |
| 3-Aminobenzamide SCHEMBL28944114 | 0.83 | PBRM1 (0.61) | PBRM1MAPTPARP1F2PLG | |
| 3-Aminobenzamide SCHEMBL28015741 | 0.83 | PBRM1 (0.61) | PBRM1MAPTPARP1F2PLG | |
| 3-Aminobenzamide SCHEMBL8688920 | 0.83 | F2 (0.63) | PBRM1MAPTPARP1F2PLG | |
| SCHEMBL9403450 | 0.82 | MAPT (0.69) | PBRM1MAPTGAAF2PLG | |
| SCHEMBL29436991 | 0.82 | MAPT (0.69) | PBRM1MAPTGAAF2PLG | |
| Anthranilamide SCHEMBL2801971 | 0.81 | HSD17B10 (0.58) | MAPTGAAPARP1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019720-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998027427-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |