Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.65 |
| ▸ | LPL | P06858 | 4/20 | 0.58 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.56 |
| ▸ | RARB | P10826 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401172 | 1.00 | NR5A1 (0.65) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL8705732 | 1.00 | NR5A1 (0.65) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL8208913 | 1.00 | NR5A1 (0.65) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL29669939 | 1.00 | NR5A1 (0.65) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL2354047 | 1.00 | NR5A1 (0.65) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL7610345 | 1.00 | NR5A1 (0.65) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL7472946 | 1.00 | NR5A1 (0.65) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL2671160 | 1.00 | NR5A1 (0.65) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL1006706 | 0.98 | NR5A1 (0.61) | NR5A1LPLLIPGTRPV1MGLL | |
| SCHEMBL3039053 | 0.95 | RARB (0.60) | NR5A1LPLLIPGTRPV1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767772-B1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | SECR DEFENCE (GB) | 2000-08-30 | — | — | EP | disclosed |
| US-5853613-A | Chiral cyclohexyl compounds | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1998-12-29 | — | — | US | disclosed |
| EP-0767772-A1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000710-A1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1996-01-11 | — | — | WO | disclosed |