Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359556 | 0.86 | GSTP1 (0.35) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL138909 | 0.85 | GSTP1 (0.34) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL7906401 | 0.81 | GSTP1 (0.31) | GSTP1 | |
| SCHEMBL7188601 | 0.81 | GSTP1 (0.36) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| Hydrochloric Acid SCHEMBL4064327 | 0.80 | GSTP1 (0.36) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL5952488 | 0.79 | GSTP1 (0.31) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL3399891 | 0.78 | — | — | |
| SCHEMBL1241164 | 0.78 | GSTP1 (0.34) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL5951685 | 0.78 | HDAC4 (0.35) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL5951992 | 0.78 | GSTP1 (0.34) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968158-A1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | Basell Polyolefine GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998040331-A1 | PREPARATION OF PREPARING SUBSTITUTED INDANONES | TARGOR GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |