Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391972 | 0.93 | MTOR (0.81) | MTORAKT1 | |
| SCHEMBL391973 | 0.93 | MTOR (0.81) | MTORAKT1 | |
| SCHEMBL18433996 | 0.89 | MTOR (0.71) | MTORAKT1 | |
| SCHEMBL2902969 | 0.87 | AKT1 (0.88) | MTORAKT1 | |
| SCHEMBL4913107 | 0.87 | AKT1 (0.88) | MTORAKT1 | |
| SCHEMBL10225247 | 0.84 | MTOR (0.82) | MTORAKT1 | |
| SCHEMBL8212095 | 0.83 | MTOR (0.80) | MTORAKT1 | |
| SCHEMBL8216670 | 0.83 | MTOR (1.00) | MTORAKT1 | |
| SCHEMBL2900173 | 0.83 | MTOR (1.00) | MTORAKT1 | |
| SCHEMBL2906097 | 0.83 | MTOR (1.00) | MTORAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023161-A1 | 2-METHYLMORPHOLINE PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |