Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18418529 | 1.00 | TLR4 (0.37) | TLR4CYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL4799538 | 1.00 | TLR4 (0.37) | TLR4CYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL4799661 | 1.00 | TLR4 (0.37) | TLR4CYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL6697654 | 0.87 | TLR4 (0.42) | TLR4CYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL5836344 | 0.87 | TLR4 (0.42) | TLR4CYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL5836340 | 0.87 | TLR4 (0.42) | TLR4CYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8215653 | 0.86 | CYP1A2 (0.52) | CYP1A2CYP2C9LMNAMAPTMEN1 | |
| SCHEMBL8220791 | 0.86 | TLR4 (0.41) | TLR4CYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL11019067 | 0.85 | TLR4 (0.41) | TLR4CYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8217513 | 0.85 | TLR4 (0.41) | TLR4CYP1A2CYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030545-A | HAVING A REDUCED VISCOSITY, A WIDE LIQUID CRYSTAL TEMPERATURE RANGE (HIGH CLEARING POINT), A HIGH CHEMICAL STABILITY (EXTREMELY HIGH SPECIFIC RESISTANCE, HIGH VOLTAGE HOLDING RATIO) AND A HIGH SOLUBILITY WITH OTHER LIQUID-CRYSTAL | CHISSO CORPORATION (JP) | 2000-02-29 | — | — | US | disclosed |