Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 7/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216974 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL8218908 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL8211990 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL8218898 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL7416250 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL8219067 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL8216970 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL8216760 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL8211988 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 | |
| SCHEMBL8218903 | 1.00 | IL6ST (0.53) | IL6STSTAT3PIK3CDPRKCASPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621270-B1 | Piperazine derivatives as collagenase inhibitors | SANKYO CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5643908-A | ANGIOGENESIS INHIBITOR, ANTITUMOR | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0621270-A1 | COLLAGENASE INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1994-10-26 | — | — | EP | disclosed |