Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 7/20 | 0.44 |
| ▸ | MMP13 | P45452 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284223 | 0.89 | TSHR (0.57) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL14284147 | 0.78 | TSHR (0.58) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL14284657 | 0.78 | TSHR (0.58) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL14284132 | 0.77 | TSHR (0.57) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL14284149 | 0.77 | TSHR (0.57) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL14284661 | 0.77 | TSHR (0.54) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL14284140 | 0.77 | TSHR (0.54) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL14284142 | 0.75 | TSHR (0.55) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL8225598 | 0.75 | TSHR (0.41) | PARP1TSHRMAOAMMP8MMP13 | |
| SCHEMBL10210165 | 0.74 | TSHR (0.56) | PARP1TSHRMAOAMMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002671-A2 | METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-01-03 | — | — | WO | disclosed |