SCHEMBL821769

SCHEMBL821769

COc1cc(NC(=O)c2ccccc2)nc(NC(=O)c2ccccc2)n1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.64
MAPT P10636 3/20 0.64
NPC1 O15118 5/20 0.58
RAB9A P51151 5/20 0.58
TP53 P04637 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58
ALDH1A1 P00352 1/20 0.56
CASP3 P42574 1/20 0.56
SENP8 Q96LD8 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
ADORA1 P30542 2/20 0.52
MEN1 O00255 3/20 0.51
ADORA3 P0DMS8 2/20 0.51
CYP1A2 P05177 3/20 0.50
GLA P06280 1/20 0.49
F2 P00734 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15308171 0.94 NPC1 (0.69) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL15305767 0.94 NPC1 (0.69) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL15305754 0.94 KMT2A (0.57) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL15305766 0.94 KMT2A (0.57) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL15305732 0.91 KMT2A (0.55) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL15305749 0.91 KMT2A (0.55) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL15305747 0.90 KMT2A (0.54) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL15308198 0.90 NPC1 (0.60) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL2623119 0.89 KMT2A (0.58) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL823170 0.87 NPC1 (0.76) KMT2AMAPTNPC1RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190235316-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2019-08-01 US disclosed
US-9971068-B2 Cellulose acylate film, polarizing plate, liquid crystal display device FUJIFILM CORPORATION (JP) 2018-05-15 US disclosed
US-9971068-B2 Cellulose acylate film, polarizing plate, liquid crystal display device FUJIFILM CORPORATION (JP) 2018-05-15 US disclosed
US-9703008-B2 Optical film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-11 US disclosed
US-9703008-B2 Optical film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-11 US disclosed
US-9656969-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-9656969-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-9523794-B2 Optical film of cellulose ester and cellulose ether for vertical alignment liquid crystal displays Konica Minolta, Inc. (JP) 2016-12-20 US disclosed
US-9523794-B2 Optical film of cellulose ester and cellulose ether for vertical alignment liquid crystal displays Konica Minolta, Inc. (JP) 2016-12-20 US disclosed
US-20160291212-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed