Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415751 | 0.87 | GLA (0.67) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL7694058 | 0.85 | GLA (0.65) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL19574225 | 0.82 | ATM (0.75) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL6043075 | 0.82 | GLA (0.61) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL5451707 | 0.82 | GLA (0.61) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL294529 | 0.80 | GLA (0.59) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL5452859 | 0.80 | GLA (0.59) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL2947983 | 0.80 | GLA (0.64) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL20520314 | 0.80 | GLA (0.64) | GLARAB9AL3MBTL1LMNATSHR | |
| SCHEMBL1447126 | 0.80 | GLA (0.59) | GLARAB9AL3MBTL1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020110126-A1 | AGONISTS OF PPAR-δ | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2020-06-04 | — | — | WO | disclosed |
| WO-2013075227-A1 | β-GLUCOCEREBROSIDASE CHAPERONES | THE HOSPITAL FOR SICK CHILDREN (CA) | 2013-05-30 | — | — | WO | disclosed |
| EP-2036895-A1 | HSP90 INHIBITOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008045688-A1 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-17 | — | — | WO | disclosed |