SCHEMBL821807

SCHEMBL821807

CCCCCN1/C(=C/C=C2/C(Cl)=C(/C=C/c3sc4c5ccccc5ccc4[n+]3CCCCC)c3ccccc32)Sc2c1ccc1ccccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 8/20 0.67
PRMT5 O14744 2/20 0.57
CARM1 Q86X55 2/20 0.57
PRMT8 Q9NR22 1/20 0.57
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821449 0.87 PRMT1 (0.61) PRMT1PRMT5CARM1PRMT8
SCHEMBL16867334 0.85 PRMT1 (0.92) PRMT1PRMT5CARM1PRMT8KDM4E
SCHEMBL821172 0.84 PRMT1 (0.58) PRMT1PRMT5CARM1PRMT8INSR
SCHEMBL14597381 0.83 PRMT1 (0.65) PRMT1PRMT5CARM1PRMT8CYP1A2
SCHEMBL14597389 0.83 PRMT1 (0.84) PRMT1PRMT5CARM1PRMT8CYP1A2
SCHEMBL70116 0.83 PRMT1 (0.84) PRMT1PRMT5CARM1PRMT8CYP1A2
SCHEMBL70101 0.82 PRMT1 (0.72) PRMT1PRMT5CARM1PRMT8CYP1A2
SCHEMBL72325 0.81 PRMT1 (1.00) PRMT1PRMT5CARM1PRMT8KDM4E
SCHEMBL10819530 0.76 PRMT1 (0.66) PRMT1PRMT5CARM1PRMT8CYP1A2
SCHEMBL14597394 0.76 PRMT1 (0.58) PRMT1PRMT5CARM1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778590-B2 Lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2014-07-15 US disclosed
US-20110287364-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-11-24 US disclosed