Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PMM2 | O15305 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210572 | 0.92 | NOTUM (0.52) | NOTUMPLA2G10ELANELMNAMAPT | |
| SCHEMBL8218340 | 0.92 | NOTUM (0.44) | NOTUMPLA2G10ELANELMNAMAPT | |
| SCHEMBL3967256 | 0.89 | ELANE (0.49) | NOTUMELANE | |
| SCHEMBL8210565 | 0.85 | ELANE (0.43) | NOTUMELANELMNAMAPT | |
| SCHEMBL8065817 | 0.84 | ELANE (0.42) | NOTUMELANELMNAMAPTGAA | |
| SCHEMBL8221794 | 0.84 | ELANE (0.42) | NOTUMELANELMNAMAPTPOLB | |
| SCHEMBL8220444 | 0.83 | NOTUM (0.53) | NOTUMELANELMNAMAPTCYP1A2 | |
| SCHEMBL8237728 | 0.83 | ELANE (0.41) | NOTUMELANELMNAMAPTGAA | |
| SCHEMBL8065761 | 0.83 | KDM4E (0.42) | NOTUMELANELMNAMAPTGAA | |
| SCHEMBL8223929 | 0.81 | DRD3 (0.42) | ELANEMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030158-A1 | MULTIMERIC HETEROCYCLIC COMPOUNDS USEFUL AS NEUTROPHIL ELASTASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | WO | disclosed |